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Grant Opportunities for Essential Hospitals

America’s Essential Hospitals created this grant tracker as a resource for our members. We regularly review private and government grants for opportunities that align with the missions of essential hospitals. Check this page often for new opportunities and use the “More Info” buttons to see the full details of each grant.

Current Grant Opportunities

Request for Proposals: Multigenerational Approach to Opioid Use Disorder Prevention and Recovery Support at Essential Hospitals

This funding opportunity will support up to five members of America’s Essential Hospitals as they participate in Essential Hospitals Institute’s Multigenerational Approach to Opioid Use Disorder Prevention and Recovery Support Learning Collaborative to improve opioid use disorder (OUD) recovery and prevention services and programming for affected populations. In partnership with the Foundation for Opioid Response Efforts (FORE), the Institute—the research, education, dissemination, and leadership development arm of America’s Essential Hospitals—will establish and facilitate a learning collaborative among grantees to support peer-to-peer learning, specifically to improve multigenerational care and support within OUD prevention and recovery services and enhance hospitals’ capabilities to provide this care.

Funding Amount:

$10,000

application period:

April 15, 2026 to May 15, 2026 at 11:59pm ET

contact email:

GrantsandContracts@essentialhospitals.org


Connecting Communities to Care: Essential Hospitals and Mobile Health

With support from the Leon Lowenstein Foundation, the Essential Hospitals Institute will convene an eight-month virtual learning collaborative to support America’s Essential Hospitals members in strengthening mobile health delivery, with an emphasis on rural communities. Participating hospitals will engage in monthly peer learning, expert-led training, and collaborative problem-solving around mobile van programs. This opportunity is limited to member hospitals operating in New Mexico, Arizona, Texas, Oklahoma, Missouri, Louisiana, and Arkansas.

Funding Amount:

$10,000

application period:

March 16, 2026 to April 17, 2026 at 11:59pm ET

contact email:

GrantsandContracts@essentialhospitals.org


Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement 

Seeking to fund studies that address high-impact methodological gaps in patient-centered comparative clinical effectiveness research (CER) including methods to support the use of patient-centered measurement, the use of real-world data (RWD) in multi-site patient-centered CER, methods to improve the use of artificial intelligence (AI) and machine learning (ML) in patient-centered CER, and methods to improve study design in patient-centered CER. 

Funding Amount:

Up to $12 million for up to 3 years based on needs of the proposed project. 

letters of intent period:

Deadline is April 28, 2026 at 5 pm (ET) 

contact email:

pfa@pcori.org


Advancing the Science of Engagement in Research PCORI Funding Announcement  

Seeking to fund projects focused on engagement of partners in research, i.e., the lifecycle of planning, conducting, and disseminating research projects. This includes studies that build an evidence base on engagement in research, including measures to capture structure or context, process, and outcomes of engagement in research, and techniques that lead to effective engagement in research.  

Funding Amount:

See guidelines on website.

letters of intent period:

Deadline is April 28, 2026 at 5 pm (ET).

contact email:

pfa@pcori.org


Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement  

Seeks to fund research that aims to fill pertinent evidence gaps representing decisional dilemmas for patients, caregivers, clinicians, policymakers and other healthcare system stakeholders, with a goal of generating evidence that helps patients and members of the broader health and healthcare community make informed decisions about their health care and health outcomes. 

Funding Amount:

Up to $120 million for up to 6.5 years based on needs of the proposed project. 

letters of intent period:

Deadline is April 28, 2026 at 5 pm (ET).

contact email:

pfa@pcori.org


Broad Pragmatic Studies PCORI Funding Announcement   

PCORI seeks proposals that compare clinical interventions and healthcare delivery system interventions to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.    

Funding Amount:

Varied for up to 5 years.

letters of intent period:

Deadline is April 28, 2026 at 5 pm (ET).

contact email:

pfa@pcori.org


This opportunity seeks applications that propose to study the ethical, legal and social implications (ELSI) of human genetic or genomic research. 

Funding Amount:

Not applicable.

Application period:

Deadline is November 19, 2026. 

contact email:

GrantsInfo@nih.gov