America’s Essential Hospitals created this grant tracker as a resource for our members. We regularly review private and government grants for opportunities that align with the missions of essential hospitals. Check this page often for new opportunities and use the “More Info” buttons to see the full details of each grant.
Current Grant Opportunities
Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement
Seeking to fund studies that address high-impact methodological gaps in patient-centered comparative clinical effectiveness research (CER) including methods to support the use of patient-centered measurement, the use of real-world data (RWD) in multi-site patient-centered CER, methods to improve the use of artificial intelligence (AI) and machine learning (ML) in patient-centered CER, and methods to improve study design in patient-centered CER.
Funding Amount:
Up to $12 million for up to 3 years based on needs of the proposed project.
letters of intent period:
Deadline is April 28, 2026 at 5 pm (ET)
contact email:
Advancing the Science of Engagement in Research PCORI Funding Announcement
Seeking to fund projects focused on engagement of partners in research, i.e., the lifecycle of planning, conducting, and disseminating research projects. This includes studies that build an evidence base on engagement in research, including measures to capture structure or context, process, and outcomes of engagement in research, and techniques that lead to effective engagement in research.
Funding Amount:
See guidelines on website.
letters of intent period:
Deadline is April 28, 2026 at 5 pm (ET).
contact email:
Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement
Seeks to fund research that aims to fill pertinent evidence gaps representing decisional dilemmas for patients, caregivers, clinicians, policymakers and other healthcare system stakeholders, with a goal of generating evidence that helps patients and members of the broader health and healthcare community make informed decisions about their health care and health outcomes.
Funding Amount:
Up to $120 million for up to 6.5 years based on needs of the proposed project.
letters of intent period:
Deadline is April 28, 2026 at 5 pm (ET).
contact email:
Broad Pragmatic Studies PCORI Funding Announcement
PCORI seeks proposals that compare clinical interventions and healthcare delivery system interventions to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.
Funding Amount:
Varied for up to 5 years.
letters of intent period:
Deadline is April 28, 2026 at 5 pm (ET).
contact email:
NIH – Ethical, Legal and Social Implications Research
This opportunity seeks applications that propose to study the ethical, legal and social implications (ELSI) of human genetic or genomic research.
Funding Amount:
Not applicable.
Application period:
Deadline is November 19, 2026.