The Patient-Centered Outcomes Research Institute (PCORI) will award up to $90 million through a new funding opportunity aimed at comparing the relative effectiveness of two or more alternatives for improving patient-centered outcomes.

The “Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes” funding can focus on any relevant topic, but PCORI has chosen 16 high-priority topics and research questions that will be given first consideration.

PCORI will hold an informational town hall session on Oct. 17 at noon for interested applicants. Letters of intent are due Oct. 31 by 5 pm ET. Full applications are due Feb. 6, 2018, at 5 pm ET.