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Buy Methylprednisolone (Medrol) Online

Where to buy Methylprednisolone

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Methylprednisolone is a corticosteroid (glucocorticosteroid) used orally and injectably (IM and IV).


Malformative appearance

  • The data published in pregnant women treated with corticosteroids in the 1st trimester of pregnancy, regardless of the molecule and the route of administration, are reassuring (the data are numerous and the reduction in use is important). It can be considered to date that the occurrence of facial slits evoked with corticosteroids by the general route is not retained.

Fetal and neonatal aspect

  • The placental passage of methylprednisolone is of the order of 40%.
  • Intrauterine growth delays and low birth weights have been reported in children of mothers treated with long-term corticosteroids, in particular by general route in the context of chronic pathologies (lupus, asthma, organ transplant...). The proper role of these pathologies cannot be excluded.
  • An impact on the fetal and neonatal adrenal gland is theoretically possible with all corticosteroids administered to the mother by the general route at the end of pregnancy.
  • However, the impact on the neonatal adrenal gland is unlikely with maintenance dose treatment (from 4 to 12 mg/d) with methylprednisolone during pregnancy.


In anticipation of pregnancy / In preconception

  • As with any chronic pathology, a preconception consultation is desirable, in order to ensure the correct therapeutic balance of the disease concerned before pregnancy.
  • It is not justified to stop or modify a treatment with methylprednisolone, whatever its route of administration.

Discovery of pregnancy during treatment

  • Reassure the patient about the malformative risk of methylprednisolone.
  • If treatment is to be continued, see "Treating a pregnant woman".

Treating a pregnant woman

  • Methylprednisolone can be used in an effective dosage, regardless of the term of pregnancy, the route of administration (including bolus) and the duration of treatment.
  • If treatment with methylprednisolone is continued until delivery, inform the team caring for the newborn in principle (see State of Knowledge).


  • The amount of methylprednisone ingested via milk is very small: the child receives about 1% of the maternal dose (in mg/kg).
  • The elimination half-life of methylprednisolone in milk is approximately 2 hours.
  • No particular events have been reported to date in children breastfed by mothers taking methylprednisolone.

In view of these elements :

By injection (IM or IV): it is preferable to wait about 4 hours after an injection before putting the child back to the breast (2 half-lives).

By mouth :

  • up to 60 mg/d, the use of methylprednisolone is possible during breastfeeding.
  • beyond 60 mg / d for a period of more than a week or in the case of very high doses (500 to 1000 mg / d), it is preferable to wait about 4 hours after taking before putting the child back to the breast (2 half-lives).

This information tells you what you should know about Methylprednisolone, including what it is used for, how to take it, its side effects, and when to call your health care provider.

What is Methylprednisolone used for?

Methylprednisolone is used for many health problems such as allergy signs, asthma, adrenal gland problems, blood problems, skin rashes or swelling problems. This is not a complete list of all health problems for which Methylprednisolone may be used. Consult the doctor.

What do I need to tell my doctor before taking Methylprednisolone?

All the presentations:

  • If you have an allergy to Methylprednisolone, any part of Methylprednisolone no prescription, or other medicines, foods, or substances. Tell your doctor about this allergy and what symptoms you have had.
  • If you have any of the following health problems: a fungal infection or a brain infection caused by malaria.
  • If you have herpes infection in the eye.
  • If you have damage to a nerve in the eye.

Injection (if applied to the muscle):

  • If you have idiopathic thrombocytopenic purpura (ITP).

This is not a list of all medicines or disorders that may interact with Methylprednisolone.

Tell your doctor and pharmacist about Medrol you take (whether prescription or over-the-counter, natural products, vitamins) and any medical conditions you have. You should check that it is safe for you to take Methylprednisolone along with all your other medicines and disorders. Do not start, stop, or change the dose of any medicine without first talking to your doctor.

What should I know or do while taking Methylprednisolone?

All the presentations:

  • Tell all of your health care providers that you take Methylprednisolone. This includes doctors, nurses, pharmacists and dentists.
  • Monitor blood function as directed by the doctor. Consult the doctor.
  • Methylprednisolone may affect skin tests to diagnose allergies. Tell the doctor and biochemists that you are taking Methylprednisolone.
  • You may be more likely to get an infection. Wash your hands often. Stay away from people who have infections, colds or flu.
  • Call your doctor right away if you notice signs of infection such as fever, chills, signs of the flu, very bad sore throat, ear or sinus pain, cough, increased sputum or change in sputum color, painful urination, mouth sores, or a wound that won't heal.
  • Chickenpox and rubella can be very serious, and even fatal, in people who take steroid medicines such as Methylprednisolone generic. Avoid being around people with chickenpox or rubella if you have not had those health problems before. If you have been exposed to chickenpox or rubella, talk to your doctor.
  • Methylprednisolone decreases the amount of natural steroids produced by the body. Tell the doctor if you have a fever, an infection, surgery, or injury. It can affect the body's natural response to this type of pressure. You may need additional doses of steroids.
  • Long-term use may increase the chances of developing cataracts or glaucoma. Talk to the doctor.
  • Methylprednisolone may cause weak bones (osteoporosis) with long-term use. Talk to your doctor to see if you have an increased risk of weak bones or if you have questions.
  • Check with your doctor before getting immunizations. The use of some vaccines with Methylprednisolone may increase the chances of infections or make the vaccine ineffective.
  • If you are diabetic, carefully monitor your blood sugar level.
  • Consult your doctor before drinking alcohol.
  • It is very uncommon for liver problems to occur with Methylprednisolone. Sometimes this caused death. Call your doctor at once if you have signs of liver problems, such as dark-colored urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, vomiting, or yellowish skin or eyes.
  • If you are 65 years of age or older, use Methylprednisolone carefully. It may cause more side effects.
  • Methylprednisolone may affect the growth of children and teenagers in some cases. They may need regular growth checks. Consult the doctor.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You will need to talk about the risks and benefits for you and the baby.


  • Very serious health problems have occurred when drugs like this are given into the spine (via epidural). These include paralysis, vision loss, strokes, and sometimes death.
  • It is unknown whether drugs like this are safe and effective if administered into the spine. This use is not approved for Medrol generic. Consult the doctor.
  • Some products contain benzyl alcohol. Do not give benzyl alcohol products to a newborn or an infant. Talk to the doctor to see if this product has benzyl alcohol in its composition.

What are the side effects that I should call my doctor about right away?

WARNING/CAUTION: Although it is very rare, some people can suffer very serious side effects, even causing death, when taking a medicine. If you experience any of the following signs or symptoms that may be related to a very serious side effect, report them to your doctor or get medical help right away:

  • Signs of an allergic reaction such as rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat;
  • trouble breathing, swallowing, or speaking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Symptoms of high blood sugar levels, such as confusion, drowsiness, unusual thirst or hunger, more frequent urination, hotness, rapid breathing, or fruity-smelling breath.
  • Symptoms of Cushing's syndrome such as weight gain in the upper back or abdomen, rounded face, very bad headache or slow healing.
  • Symptoms of a weak adrenal gland, such as very severe nausea or vomiting, severe dizziness or fainting, muscle weakness, feeling tired, mood changes, decreased appetite, or weight loss.
  • Symptoms of low potassium levels such as muscle pain or weakness, muscle cramps, or a pulse that doesn't feel normal.
  • Symptoms of a problem with the pancreas (pancreatitis) such as very bad stomach pain, very bad back pain or very bad stomach upset or vomiting.
  • Signs of high blood pressure such as headaches or very severe dizziness, fainting or changes in vision.
  • Shortness of breath, a lot of weight gain, swelling in the arms or legs.
  • You are unable to urinate or noticed a change in the amount of urine.
  • Skin modifications (acne, stretch marks, slow healing, hair growth).
  • Chest pain or pressure.
  • Fast, slow, or abnormal heartbeat.
  • Changes in the period (menstrual).
  • Pain in the joints or bones.
  • Change in the view.
  • Mental, mood, or behavioral changes that are new or getting worse.
  • Seizures.
  • Unusual burning, numbness, or tingling sensation.
  • Hematoma or bleeding for no apparent reason.
  • Severe stomach pain.
  • Dark, black, or bloody stool.
  • Vomiting blood or vomit that looks like coffee beans.

What other side effects does Methylprednisolone have?

All medicines can have side effects. However, many people have no side effects at all or have only minor side effects. Call your doctor or seek medical assistance if any of these side effects bother you or do not go away:

  • Nausea or vomiting.
  • Trouble sleeping.
  • Agitation.
  • Excessive sweating.
  • Headache.

These are not all the side effects that could occur. If you have questions about side effects, call your doctor. Call the doctor for advice about side effects.

You can report the side effects to the health agency of your country.

How is Methylprednisolone best taken?

Take Methylprednisolone as directed by your doctor. Read all the information provided to you. Follow all instructions carefully.


  • If you are taking Methylprednisolone once a day, take it in the morning.
  • It should be taken with food.
  • Keep taking Methylprednisolone as directed by your doctor or other health care provider, even if you feel well.


  • Methylprednisolone is given by injection.

All the presentations:

  • Tell your doctor if you have missed a dose or have recently stopped taking Methylprednisolone and feel very tired, weak, or shaky, or have a fast heartbeat, confusion, sweating, or dizziness.
  • If you have been taking generic Methylprednisolone for several weeks, consult the doctor before stopping it. You may need to stop it gradually.
  • Have your eye pressure checked if you take cheap Methylprednisolone for a long period. Talk to your doctor.
  • Get a bone density test as directed by your doctor. Consult the doctor.
  • You may need to decrease the salt intake in your diet and take additional potassium. Talk to your doctor.

What should I do if I miss a dose?


  • Take the missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and continue with the usual schedule.
  • Do not take two doses at the same time or take additional doses.


  • Call the doctor for instructions.

How do I store or discard Methylprednisolone?


  • Store at room temperature in a dry place. Do not store in a bathroom.


  • If you need to store Methylprednisolone at home, talk to your doctor, nurse, or pharmacist about how to do it.

All the presentations:

  • Store Medrol in a safe place. Keep all medicines out of the reach of children and pets.
  • Throw away unused or expired medicines. Do not flush them down the toilet or down the drain unless instructed to do so. Ask the pharmacist if you have questions about the best way to dispose of medicines. There may be drug take-back programs in your area.

General information about Medrol

  • If your symptoms or disorders do not improve or if they get worse, call your doctor.
  • Do not share your Medrol with others or take anyone else's medicine.
  • Some medicines may have another patient information leaflet. If you have any questions about Methylprednisolone without a doctor prescription, talk to your doctor, nurse, pharmacist, or other health care provider.
  • If you think an overdose has occurred, call your local poison control center or seek medical attention right away. Be prepared to answer what was ingested, how much and when.

Use of the information by the consumer and disclaimer

This overview is a limited summary of information about diagnosis, treatment and/or medication. It is not intended to be exhaustive and should be used as a tool to help the user understand and/or evaluate possible diagnostic and treatment options. It does not include all the information about the diseases, treatments, medications, side effects or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for a healthcare provider's medical advice, diagnosis, or treatment based on the healthcare provider's examination and assessment of a patient's specific and unique circumstances. Patients should speak with a healthcare provider to get complete information about their health, medical questions, and treatment options, including any risks or benefits related to the use of medications. This information does not endorse any treatment or medication as safe, effective, or approved to treat a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use made of it. The use of this information is governed by the Terms of Use


About the Author

Shahid Zaman is a senior policy analyst at America's Essential Hospitals.

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